Philip D. Rye and Astrid Hilde Myrset joins AlgiPharma

R&D Director: Philip D. Rye, PhD

Philip Rye (1962) came to AlgiPharma in 2012. Prior to joining the company Phil was head of Biology R&D at GE Healthcare, Oslo, where he was responsible for team leadership in understanding the pharmacology of novel in vivo imaging agents and interpreting the pathophysiology of cancer, cardiovascular and neurological diseases. Phil brings a wide range of skills and expertise spanning both academic research and commercial in vitro and in vivo diagnostic development. He gained his doctorate at the Department of Pathology at University of Leicester, UK in 1990. His postdoctoral research experience from UK and Norway includes glycoconjugate biochemistry, animal models, cell biology, and biochemistry. Phil also brings more than 11 years of experience in the diagnostics and pharmaceutical industry in both research and management roles and has been involved in the successful development and launch of molecular in vitro diagnostic tests. He is inventor/co-inventor on four patents and has 37 peer reviewed articles in international medical and biochemical journals.

Director for Clinical and Pre-clinical Research: Astrid Hilde Myrset, PhD

Astrid Hilde Myrset (1956) is a biochemist by training, and joined AlgiPharma in 2012. From 2008 – 2012 Astrid was the CEO of Omegatri AS, building a start-up company within the health segment, securing funding from investors in Norway and abroad, as well from Innovation Norway and the Norwegian Research Council. The work led to the successful development of two novel products to the process of scaling up, and involved extensive partnering for regulatory work, scale up and production. From 1994 to 2008 Astrid held various positions in R&D in the pharmaceutical industry (Nycomed – Amersham– GE), most recently global positions where she worked on strategy, innovation and knowledge management including project reviews, across functions, sites and geographies. Prior to this Astrid worked as a project leader, established a molecular biology lab and was involved in a range of projects in preclinical development. Astrid has an extensive network in the academia as well as the life science industry in Norway, is a member of the Board of MedCoast Scandinavia and of the Advisory board of Sintef Materials and Chemistry.

August 2012

AlgiPharma wins €4,6 million EUROSTARS grant

AlgiPharma has together with partners Smerud Medical Research and Simbec Research been awarded a EUROSTARS grant for a €4,6 million project.

July 2011

AlgiPharma wins research grant from CFF

AlgiPharma has received a research grant from CFF, the Cystic Fibrosis Foundation, to perform an in-vitro study of its proposed cystic fibrosis medicine. The grant is administered by the Cystic Fibrosis Foundation Therapeutics Inc., a subsidiary of the CFF. The research shall be performed in the United Kingdom.

About the Cystic Fibrosis Foundation: The Cystic Fibrosis Foundation is the leading organization devoted to curing and controlling cystic fibrosis. Headquartered in Bethesda, MD, USA, the Foundation funds CF research, has 80 chapter and branch offices throughout the United States, and supports and accredits a nationwide network of 115 CF care centers, which provide vital treatments and other CF resources to patients and families. For more information, visit www.cff.org.
To advance the search for a cure, CFF has invested nearly $230 million in promising scientific research in the pharmaceutical and biotechnology industries since 1998. As a result, the Foundation has nearly 30 potential therapies in its drug discovery and development pipeline. Any one of these could have a profound impact on the lives of people with cystic fibrosis.

For further information, please contact:
Yngvar P. Berg, CEO; yngvar.berg@algipharma.com

April 2011

AlgiPharma granted permission to start Phase II trials in Cystic Fibrosis

AlgiPharma has been granted permission to start its clinical phase 2 trial in cystic fibrosis patients by the Irish Medicines Board. The study title is: A double-blind, randomized, placebo-controlled, cross-over study to evaluate the safety, tolerability and preliminary efficacy of alginate oligosaccharide (OligoG) administered for 28 days in subjects with Cystic Fibrosis chronically colonised with Pseudomonas aeruginosa.

Yngvar P. Berg, CEO; yngvar.berg@algipharma.com
Astrid Hilde Myrset, Clinical Director; astrid.hilde.myrset@algipharma.com

April 2011

US Department of Defense supports an AlgiPharma initiated in vivo wound healing study on OligoG

AlgiPharma has together with Prof. Chandan Sen, at Ohio State University embarked on a study to investigate the effects of OligoG in a unique biofilm infected in vivo wound healing model.

For further information, please contact:
Philip D. Rye R&D Director; phil.rye@algipharma.com

August 2010

AlgiPharma Phase I clinical trial shows excellent safety and tolerability data for respiratory diseases

OligoG CF-5/20 was well tolerated when administered by inhalation to 28 healthy subjects. All adverse events monitored were mild and transient. No serious adverse events, no deaths, no discontinuations.

Read more ClinicalTrials.gov

For more information contact:
Yngvar P. Berg, CEO; yngvar.berg@algipharma.com
Astrid Hilde Myrset, Clinical Director; astrid.hilde.myrset@algipharma.com

January 2010

AlgiPharma granted permission to start Phase I trials in Cystic Fibrosis

A clinical phase I for AlgiPharma’s prospective medicine for Cystic Fibrosis (respiratory diseases), Oligo-G CF-5/20, was approved by the Medicines and Healthcare Product Regulatory Agency, MRHA, and is initiated at SIMBEC (UK) and scheduled to be concluded before the end of the year. Results are set to be reported in the first quarter of 2010.

For more information contact:
Yngvar P. Berg, CEO, +47 90044903; yngvar.berg@algipharma.com
Astrid Hilde Myrset, Clinical Director, +47 93026094; astrid.hilde.myrset@algipharma.com

September 2009

AlgiPharma wins NFR funding for basic research projects on biofilms

The Research Council of Norway (Norges Forskningsråd (NFR)) has awarded AlgiPharma grants for two new projects “Biofilm” and “Epipharm II” representing a continuation and expansion of the NFR support for AlgiPharma’s alginate oligomer research efforts. These grants are administered under the NFR program for User directed Innovation Arena.

For further information, please contact:
Philip D. Rye R&D Director, +47 97503033; phil.rye@algipharma.com

June 2008

AlgiPharma’s medicinal alginate product gains Orphan Drug Status for Cystic Fibrosis Treatment

AlgiPharma’s medicinal product “Alginate oligosaccharide (G-block) fragment” has been designated as an orphan medicinal product for the following indication: treatment of Cystic Fibrosis. The European Medicines Agency’s Committee for Orphan Medicinal Products recommended that AlgiPharma’s application be accepted by the Commission of the European Communities. The Commission gave final approval on September 14th.

For more information contact:
Yngvar P. Berg, CEO, +47 90044903; yngvar.berg@algipharma.com
Astrid Hilde Myrset, Clinical Director, +47 93026094; astrid.hilde.myrset@algipharma.com

September 2007

AlgiPharma Established

On the initiative of FMC BioPolymer AS, AlgiPharma was established, financed and began operating as an independent company. AlgiPharma is a biopharmaceutical company that aims to develop medicinal products within the areas of respiratory diseases, wound healing and other infectious diseases.

For further information, please contact:
Arne Dessen, Chairman of Board, +47 95170278; arne.dessen@algipharma.com
Yngvar P. Berg, CEO, +47 90044903; yngvar.berg@algipharma.com

August 2006