The purpose of the study is assessment of efficacy and safety of OligoG as a dry powder formulation, following multiple dose administration in adult subjects with cystic fibrosis, in a cross-over design. The primary objective is to demonstrate efficacy of inhaled OligoG measured by FEV1, and supported by secondary endpoints including Mucociliary Clearance, rheology,microbiology and Quality-of-Life. The secondary objectives are to demonstrate the safety and tolerability of inhaled OligoG as a dry powder for inhalation, and to evaluate patient compliance with treatment. Mucociliary and Cough Clearance (MCC) will be an exploratory endpoint in a subset of patients, and Lung Clearance Index (LCI) an exploratory endpoint in further subset of patients.
Additional details about this clinical trial are available at www.clinicaltrials.gov